Patients suffering from diabetes mellitus tend to show greater susceptibility to delayed vascular wound healing and atherosclerosis. In non-diabetic patients, atherosclerotic lesions most typically develop in regions where vessel walls are exposed to oscillatory low fluid shear stress. Previous endothelial cell (EC) culture studies have investigated wound healing under high glucose conditions and oscillatory low fluid shear stress independently. This study aims to investigate EC wound healing migration speed while under both of these conditions simultaneously to create an even more physiologically relevant diabetic model. Our experiments utilized a custom built machine capable of inducing oscillatory fluid motion on wounded cell cultures exposed to high glucose medium. Preliminary data suggests that hyperglycemic conditions and oscillatory fluid motion concurrently inhibit wound healing migration speed. However, we conclude that more data is needed to validate this result. The outcome of these experiments will pave the way for future exploration of possible therapeutic drugs that could help increase diabetic wound healing migration speeds.