Profile

My lab utilizes protein engineering and bioconjugation techniques in developing therapeutic and diagnostic platforms to enable precision medicine.  Our current research focus is on 1) controlling the systemic and cellular pharmacokinetics (PK) of antibody-based therapeutics by creating self-amplifying antibody-drug conjugates, 2) evaluating the pharmaceutic stability of antibody-based therapeutics, and 3) engineering binary/ternary complementation-based diagnostic systems that utilize luminescent reporters for detection of important biomarkers.